Efficacy of Laxative Management in Palliative Care Patients: is Polyethylene Glycol a New Option?
Wirz, Stefan, University of Bonn, Germany, Klaschik, Eberhard, Malteser Hospital, Bonn, Germany

Goal: This study aims to assess the efficacy of the use of laxatives in palliative care patients receiving an opioid therapy, with special attention to polyethylene glycol 3350/electrolytes.
Methods: This study analysed the computerised data of 206 patients using descriptive statistics. Subgroups were analysed using confirmatory statistics.
Results: Using a standardised step scheme, laxatives were resolutely given to 74.3% of patients. Constipation occurred in 42.7% of patients. Laxative use was uncomplicated in 78.4%. As a therapy for constipation, the combined administration of polyethylene glycol, sodium picosulphate and paraffin proved most effective, although statistical analysis yielded no significance.
Conclusions: A standardised assessment and therapy improves the management of constipation. In palliative care patients the early use of polyethylene glycol in a step scheme is recommended for treating opioid-relatedconstipation. There is a need of further investigation on this topic.