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The principal objective of the EPOS study is to examine clinical symptoms, pharmacogenetics and pharmacology related to the use of opioids in order to improve the scientific basis of better individual tailored pain treatment.
The EPOS study represents a translational research project with combined efforts from clinical researchers, pharmacological researchers and basic researchers. The study will include 3000 cancer patients treated with opioids for moderate or severe pain. The study recruits patients from 10 countries.
Per May 2006 The EPOS study includes 15 centers throughout Europe and has included about 1200 patients.
The international cooperation is facilitated by the participation in the study by the Research Steering Committee of the European Association for Palliative Care. The study is headed by the EPOS steering committee. The steering committee includes the principal investigator, head of pharmacological laboratory, head of genetic laboratory and one representative from each participating centre. All use of data, use of results from analyses, and use of stored blood samples will be decided by the study steering committee
The Principle investigator is Associate Professor Pål Klepstad (), Pain and Palliation Research Group, Norwegian University of Science and Technology.
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